Antigenic relationships between flaviviruses as determined by cross-neutralization tests with polyclonal antisera

J Gen Virol. 1989 Jan;70 ( Pt 1):37-43. doi: 10.1099/0022-1317-70-1-37.


The recently established virus family Flaviviridae contains at least 68 recognized members. Sixty-six of these viruses were tested by cross-neutralization in cell cultures. Flaviviruses were separated into eight complexes [tick-borne encephalitis (12 viruses), Rio Bravo (six), Japanese encephalitis (10), Tyuleniy (three), Ntaya (five), Uganda S (four), dengue (four) and Modoc (five)] containing 49 viruses; 17 other viruses were not sufficiently related to warrant inclusion in any of these complexes.

MeSH terms

  • Antigens, Viral / analysis*
  • Cross Reactions
  • Flavivirus / classification*
  • Flavivirus / immunology
  • Immune Sera / immunology
  • Neutralization Tests


  • Antigens, Viral
  • Immune Sera