The constellation of dietary factors in adolescent acne: a semantic connectivity map approach

J Eur Acad Dermatol Venereol. 2016 Jan;30(1):96-100. doi: 10.1111/jdv.12878. Epub 2014 Dec 2.


Background: Different lifestyle and dietetic factors have been linked with the onset and severity of acne.

Objective: To assess the complex interconnection between dietetic variables and acne.

Methods: This was a reanalysis of data from a case-control study by using a semantic connectivity map approach. 563 subjects, aged 10-24 years, involved in a case-control study of acne between March 2009 and February 2010, were considered in this study. The analysis evaluated the link between a moderate to severe acne and anthropometric variables, family history and dietetic factors. Analyses were conducted by relying on an artificial adaptive system, the Auto Semantic Connectivity Map (AutoCM).

Results: The AutoCM map showed that moderate-severe acne was closely associated with family history of acne in first degree relatives, obesity (BMI ≥ 30), and high consumption of milk, in particular skim milk, cheese/yogurt, sweets/cakes, chocolate, and a low consumption of fish, and limited intake of fruits/vegetables.

Conclusion: Our analyses confirm the link between several dietetic items and acne. When providing care, dermatologists should also be aware of the complex interconnection between dietetic factors and acne.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acne Vulgaris / etiology*
  • Acne Vulgaris / genetics
  • Adolescent
  • Anthropometry
  • Case-Control Studies
  • Child
  • Diet*
  • Humans
  • Risk Factors
  • Semantics
  • Severity of Illness Index
  • Young Adult