10-20-30 training increases performance and lowers blood pressure and VEGF in runners

Scand J Med Sci Sports. 2015 Oct;25(5):e479-89. doi: 10.1111/sms.12356. Epub 2014 Dec 1.

Abstract

The present study examined the effect of training by the 10-20-30 concept on performance, blood pressure (BP), and skeletal muscle angiogenesis as well as the feasibility of completing high-intensity interval training in local running communities. One hundred sixty recreational runners were divided into either a control group (CON; n = 28), or a 10-20-30 training group (10-20-30; n = 132) replacing two of three weekly training sessions with 10-20-30 training for 8 weeks and performance of a 5-km run (5-K) and BP was measured. VO2max was measured and resting muscle biopsies were taken in a subgroup of runners (n = 18). 10-20-30 improved 5-K time (38 s) and lowered systolic BP (2 ± 1 mmHg). For hypertensive subjects in 10-20-30 (n = 30), systolic and diastolic BP was lowered by 5 ± 4 and 3 ± 2 mmHg, respectively, which was a greater reduction than in the non-hypertensive subjects (n = 102). 10-20-30 increased VO2max but did not influence muscle fiber area, distribution or capillarization, whereas the expression of the pro-angiogenic vascular endothelial growth factor (VEGF) was lowered by 22%. No changes were observed in CON. These results suggest that 10-20-30 training is an effective and easily implemented training intervention improving endurance performance, VO2max and lowering BP in recreational runners, but does not affect muscle morphology and reduces muscle VEGF.

Keywords: HIT; VO2max; angiogenesis; community; health.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Athletic Performance / physiology*
  • Blood Pressure
  • Capillaries / anatomy & histology
  • Female
  • Heart Rate
  • Humans
  • Hypertension / physiopathology
  • Male
  • Middle Aged
  • Muscle, Skeletal / anatomy & histology*
  • Muscle, Skeletal / blood supply
  • Neovascularization, Physiologic
  • Oxygen Consumption
  • Physical Conditioning, Human / methods*
  • Physical Conditioning, Human / physiology*
  • Running / physiology*
  • Vascular Endothelial Growth Factor A / blood

Substances

  • Vascular Endothelial Growth Factor A