Diffusion tensor imaging for brain malformations: does it help?

Neuroimaging Clin N Am. 2014 Nov;24(4):619-37. doi: 10.1016/j.nic.2014.07.004. Epub 2014 Sep 6.


In this article, the basics of diffusion-weighted imaging/diffusion tensor imaging (DTI) are discussed, including a short historical perspective on the fiber dissection technique, followed by a review of selected brain malformations in which DTI and tractography have contributed to a better understanding of the malformations, and by a clinical case in which DTI showed a disorder of the internal neuroarchitecture that could not be correctly appreciated by conventional anatomic magnetic resonance imaging.

Keywords: Axonal guidance disorders; Brain malformations; Children; Diffusion tensor imaging; Fiber tractography; Neuroimaging.

Publication types

  • Review

MeSH terms

  • Brain / abnormalities*
  • Brain / pathology*
  • Diffusion Tensor Imaging / methods*
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • White Matter / abnormalities*
  • White Matter / pathology*