Anti-inflammatory and antioxidative activity of anthocyanins from purple basil leaves induced by selected abiotic elicitors

Food Chem. 2015 Apr 1;172:71-7. doi: 10.1016/j.foodchem.2014.09.043. Epub 2014 Sep 17.

Abstract

This paper investigates changes in the anti-inflammatory and antioxidative activity of anthocyanins from purple basil (Ocimum basilicum L.) leaves induced by arachidonic acid (AA), jasmonic acid (JA) and β-aminobutyric acid (BABA). The anthocyanins content was significantly increased by all elicitors used in this study; however, no increase was observed in the antioxidant activity of the analyzed extracts. Additionally, a significant decrease by about 50% in the ability to chelate Fe(II) was noted. Further, an increase in the potential anti-inflammatory activity of basil anthocyanins was observed after treatment with each the abiotic elicitor. The IC50 value for lipoxygenase inhibition was almost twice as low after elicitation as that of the control. Also, cyclooxygenase inhibition by anthocyanins was stimulated by abiotic elicitors, except for JA-sample. Additionally, HPLC-analysis indicated that elicitation with AA, JA and BABA caused increases in content most of all anthocyanin compounds.

Keywords: Anthocyanins; Antioxidant properties; Elicitation; Enzyme inhibition; Purple basil.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminobutyrates / pharmacology*
  • Anthocyanins / analysis
  • Anti-Inflammatory Agents / analysis*
  • Antioxidants / analysis*
  • Arachidonic Acid / pharmacology*
  • Chromatography, High Pressure Liquid
  • Cyclopentanes / pharmacology*
  • Ocimum basilicum / chemistry*
  • Ocimum basilicum / drug effects*
  • Oxylipins / pharmacology*
  • Plant Extracts / analysis*
  • Plant Leaves / chemistry
  • Plant Leaves / drug effects

Substances

  • Aminobutyrates
  • Anthocyanins
  • Anti-Inflammatory Agents
  • Antioxidants
  • Cyclopentanes
  • Oxylipins
  • Plant Extracts
  • Arachidonic Acid
  • 3-aminobutyric acid
  • jasmonic acid