Keratitis caused by Absidia corymbifera in an immunocompetent male with no corneal injuries
Arch Soc Esp Oftalmol. 2015 Mar;90(3):139-41.
doi: 10.1016/j.oftal.2014.02.020.
Epub 2014 Nov 18.
[Article in
English,
Spanish]
Affiliations
- 1 FEA oftalmología,.Unidad de Superficie ocular y Córnea., Hospital La Mancha Centro, Alcázar de San Juan, Ciudad Real, España. Electronic address: dimeva23@hotmail.com.
- 2 FEA oftalmología,.Unidad de Superficie ocular y Córnea., Hospital La Mancha Centro, Alcázar de San Juan, Ciudad Real, España.
- 3 MIR oftalmología, Hospital La Mancha Centro, Alcázar de San Juan, Ciudad Real, España.
- 4 FEA oftalmología. Unidad de Motilidad ocular y estrabismo, Hospital La Mancha Centro, Alcázar de San Juan, Ciudad Real, España.
Abstract
Case Report A healthy 55-years-old male went to emergency due to a white infiltrate in the left eye without corneal trauma which partially responds to antibiotic treatment. The infiltrate worsened by the use of topical steroids. Direct microscopic evaluation and Gram stain are a valuable diagnostic tool for the detection of Absidia filaments. There is a successful treatment with anphotericin and posaconazole. Discussion Keratitis caused by Zygomicetes are unusual. This is a rare condition in healthy patients with no corneal trauma. The treatment with amphotericin and posaconazole are synergistic against filamentous fungi.
Keywords:
Absidia corymbifera; Amphotericin; Anfotericina; Fungal keratitis; Queratitis fúngica.
Copyright © 2013 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.
MeSH terms
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Absidia / drug effects
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Absidia / isolation & purification*
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Administration, Ophthalmic
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Adrenal Cortex Hormones / adverse effects
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Amphotericin B / therapeutic use
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Anti-Bacterial Agents / therapeutic use
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Antifungal Agents / therapeutic use
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Combined Modality Therapy
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Corneal Transplantation
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Corneal Ulcer / drug therapy
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Corneal Ulcer / etiology*
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Corneal Ulcer / microbiology
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Corneal Ulcer / surgery
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Drug Therapy, Combination
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Humans
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Immunocompetence
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Male
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Middle Aged
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Mucormycosis / diagnosis
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Mucormycosis / drug therapy
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Mucormycosis / microbiology*
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Ophthalmic Solutions
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Staining and Labeling
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Triazoles / therapeutic use
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Voriconazole / therapeutic use
Substances
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Adrenal Cortex Hormones
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Anti-Bacterial Agents
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Antifungal Agents
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Ophthalmic Solutions
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Triazoles
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posaconazole
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Amphotericin B
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Voriconazole