Primary adnexal angiosarcoma masquerading as periorbital hematoma

Surv Ophthalmol. 2014 Nov-Dec;59(6):655-9. doi: 10.1016/j.survophthal.2014.06.005. Epub 2014 Jul 2.

Abstract

We report an elderly woman who was anticoagulated and presented with a recent history of right-sided orbital contusion and a periorbital hematoma without clinical or radiological evidence of focal mass or orbital involvement. She was initially treated conservatively. Continued progression of adnexal swelling and erythema prompted further investigation, however. There was no improvement with surgical drainage alone; biopsy revealed angiosarcoma. The discovery of this vascular tumor underscores the importance of a reconsideration of the diagnosis in the face of counterintuitive findings. Additionally, we emphasize the need to consider malignancy in the differential diagnosis of prolonged periorbital swelling, regardless of a history of recent trauma.

Keywords: angiosarcoma; primary adnexal angiosarcoma.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Biomarkers, Tumor / metabolism
  • Biopsy
  • Diagnosis, Differential
  • Eyelid Neoplasms / diagnosis*
  • Eyelid Neoplasms / metabolism
  • Eyelid Neoplasms / surgery
  • Female
  • Hemangiosarcoma / diagnosis*
  • Hemangiosarcoma / metabolism
  • Hemangiosarcoma / surgery
  • Hematoma / diagnosis*
  • Hematoma / metabolism
  • Hematoma / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Neoplasm Proteins / metabolism
  • Ophthalmologic Surgical Procedures
  • Orbital Diseases / diagnosis*
  • Orbital Diseases / metabolism
  • Orbital Diseases / surgery
  • Parotid Neoplasms / diagnosis
  • Parotid Neoplasms / surgery
  • Radiotherapy, Adjuvant
  • Tomography, X-Ray Computed

Substances

  • Biomarkers, Tumor
  • Neoplasm Proteins