Fatal hepatic necrosis caused by disseminated type 5 adenovirus infection in a renal transplant recipient

Am J Nephrol. 1989;9(2):101-5. doi: 10.1159/000167945.

Abstract

This is an unusual case of fatal hepatic necrosis caused by disseminated type 5 adenovirus in a renal transplant recipient. This adult patient may have been colonized at the time of transplantation with a kidney from a pediatric donor. The adenovirus became invasive when the host's cellular immune system was suppressed by high doses of corticosteroids given to reverse acute allograft rejection.

Publication types

  • Case Reports

MeSH terms

  • Adenoviridae Infections / complications*
  • Adenovirus Infections, Human / complications*
  • Female
  • Graft Rejection
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Immunosuppressive Agents / therapeutic use
  • Kidney Transplantation*
  • Liver / pathology*
  • Liver Diseases / etiology*
  • Liver Diseases / pathology
  • Middle Aged
  • Necrosis
  • Opportunistic Infections / complications*

Substances

  • Immunosuppressive Agents