Bilateral parotid gland metastases from carcinoma of the breast that presented 25 years after initial treatment

Br J Oral Maxillofac Surg. 2015 Jan;53(1):94-6. doi: 10.1016/j.bjoms.2014.09.023. Epub 2014 Oct 18.

Abstract

We report a case of a 76-year-old woman with metastases to both parotid glands almost 25 years after mastectomy and chemotherapy for primary carcinoma of the breast. Immunohistochemical staining is invaluable in establishing the origin of metastatic deposits, in this case, expression of oestrogen receptors in a previously resected adenocarcinoma of the breast. The information can be used to target treatment accurately in selected cases of advanced malignancy.

Keywords: Bilateral parotid metastases; Breast adenocarcinoma; Cytokeratins; Immunohistochemistry; Letrozole; Tamoxifen.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / chemistry
  • Adenocarcinoma / pathology
  • Adenocarcinoma / secondary*
  • Aged
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Breast Neoplasms / pathology*
  • Chemotherapy, Adjuvant
  • Female
  • Follow-Up Studies
  • Humans
  • Mastectomy / methods
  • Parotid Neoplasms / pathology
  • Parotid Neoplasms / secondary*
  • Receptors, Estrogen / analysis
  • Tamoxifen / therapeutic use

Substances

  • Antineoplastic Agents, Hormonal
  • Receptors, Estrogen
  • Tamoxifen