Historic overview of allergy research in the Netherlands

Rob C Aalberse; Edward F Knol

doi:10.1016/j.imlet.2014.10.015

Historic overview of allergy research in the Netherlands

Immunol Lett. 2014 Dec;162(2 Pt B):163-72. doi: 10.1016/j.imlet.2014.10.015. Epub 2014 Oct 18.

Authors

Rob C Aalberse¹, Edward F Knol²

Affiliations

¹ Department of Immunopathology, Sanquin Blood Supply Foundation and Academic Medical Centre, Amsterdam, The Netherlands.
² Department of Immunology, University Medical Center Utrecht, The Netherlands; Department of Dermatology and Allergology, University Medical Center Utrecht, The Netherlands. Electronic address: e.f.knol@umcutrecht.nl.

PMID: 25455604
DOI: 10.1016/j.imlet.2014.10.015

Abstract

Research in allergy has a long history in the Netherlands, although the relation with immunology has not always been appreciated. In many aspects Dutch researchers have made major contribution in allergy research. This ranges from the first characterization of house dust mite as an important allergen, the first characterization of human Th2 and Th1 T cell clones, to the development of diagnostic test systems. In this overview Aalberse and Knol have made an overview of the major contributions of Dutch immunologists in allergy.

Keywords: Allergens; Allergy; Basophils; Eosinophils; IgE; Th2 lymphocytes.

Publication types

Historical Article
Research Support, Non-U.S. Gov't
Review

MeSH terms

Allergens / immunology*
Animals
Biomedical Research / history*
History, 20th Century
History, 21st Century
Humans
Hypersensitivity* / diagnosis
Hypersensitivity* / history
Hypersensitivity* / immunology
Th1 Cells / immunology*
Th2 Cells / immunology*

Substances

Allergens