Neurobiology: Reelin mediates form and function

Curr Biol. 2014 Nov 17;24(22):R1089-92. doi: 10.1016/j.cub.2014.10.012. Epub 2014 Nov 17.


Reelin choreographs neuronal migration to establish laminar structures during brain formation. A recent paper uncovers a new function for Reelin signaling in specifying dendritic compartmentalization. Reelin-induced tyrosine phosphorylation is responsible for enrichment of ion channels in dendritic tufts.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Adhesion Molecules, Neuronal / metabolism*
  • Dendrites / metabolism*
  • Extracellular Matrix Proteins / metabolism*
  • Nerve Tissue Proteins / metabolism*
  • Neurons / metabolism*
  • Serine Endopeptidases / metabolism*


  • Cell Adhesion Molecules, Neuronal
  • Extracellular Matrix Proteins
  • Nerve Tissue Proteins
  • Serine Endopeptidases