Potential treatments for food allergy

Stephanie Albin; Anna Nowak-Węgrzyn

doi:10.1016/j.iac.2014.09.011

Potential treatments for food allergy

Immunol Allergy Clin North Am. 2015 Feb;35(1):77-100. doi: 10.1016/j.iac.2014.09.011. Epub 2014 Nov 21.

Authors

Stephanie Albin¹, Anna Nowak-Węgrzyn²

Affiliations

¹ Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1198, New York, NY 10029, USA.
² Division of Allergy and Immunology, Department of Pediatrics, Kravis Children's Hospital, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1198, New York, NY 10029, USA. Electronic address: anna.nowak-wegrzyn@mssm.edu.

PMID: 25459578
DOI: 10.1016/j.iac.2014.09.011

Abstract

This article presents an overview of potential treatments of food allergy, with an emphasis on various forms of immunotherapy (including oral immunotherapy, sublingual immunotherapy, epicutaneous immunotherapy, immunotherapy with modified food antigens, and immunotherapy with a recombinant peanut vaccine). Allergen nonspecific treatments, such as Chinese herbal formulas, probiotics/prebiotics, helminths, monoclonal antibodies, and toll-like receptor agonists, are also summarized.

Keywords: Desensitization; Food allergy; Food immunotherapy; Omalizumab; Tolerance.

Publication types

Review

MeSH terms

Allergens / immunology
Animals
Anti-Allergic Agents / therapeutic use*
Antibodies, Anti-Idiotypic / therapeutic use*
Antibodies, Monoclonal, Humanized / therapeutic use*
Desensitization, Immunologic / methods*
Food Hypersensitivity / therapy*
Helminths / immunology
Humans
Immune Tolerance / drug effects*
Immunologic Factors / therapeutic use
Omalizumab
Probiotics / therapeutic use
Toll-Like Receptors / agonists

Substances

Allergens
Anti-Allergic Agents
Antibodies, Anti-Idiotypic
Antibodies, Monoclonal, Humanized
Immunologic Factors
Toll-Like Receptors
Omalizumab