Correlation of C-reactive protein and body mass index with diabetic retinopathy in Indian population

Dipayan Sen; Sambuddha Ghosh; Debesh Roy

doi:10.1016/j.dsx.2014.05.004

Correlation of C-reactive protein and body mass index with diabetic retinopathy in Indian population

Diabetes Metab Syndr. 2015 Jan-Mar;9(1):28-9. doi: 10.1016/j.dsx.2014.05.004. Epub 2014 May 29.

Authors

Dipayan Sen¹, Sambuddha Ghosh², Debesh Roy¹

Affiliations

¹ Regional Institute of Ophthalmology and Department of Biochemistry, Medical College, 88 College Street, Kolkata 700073, India.
² Regional Institute of Ophthalmology and Department of Biochemistry, Medical College, 88 College Street, Kolkata 700073, India. Electronic address: sambuddhaghosh@gmail.com.

PMID: 25470633
DOI: 10.1016/j.dsx.2014.05.004

Abstract

Background: Association of C-reactive protein (CRP) and body mass index (BMI) with diabetic retinopathy (DR) has conflicting reports.

Method: Sixty diabetes patients each with DR (Group A), no DR (Group B) and 60 healthy volunteers (control, group C) were studied. CRP was measured. BMI was calculated.

Result: Significant difference in CRP was observed between groups A & B (p=0.000) and A & C (p=0.007). No significant difference in BMI was observed. Central macular thickness correlated positively with CRP and negatively with BMI.

Conclusion: We observed strong association of CRP with DR and no significant relationship between DR and BMI.

Keywords: Body mass index; C-reactive protein; Diabetic retinopathy.

Publication types

Observational Study
Research Support, Non-U.S. Gov't

MeSH terms

Body Mass Index
C-Reactive Protein / metabolism*
Diabetic Retinopathy / blood*
Diabetic Retinopathy / epidemiology*
Diabetic Retinopathy / ethnology
Female
Humans
India / epidemiology
Male
Middle Aged
Predictive Value of Tests
Prevalence
Risk Factors
White People*

Substances

C-Reactive Protein