Aims: To evaluate technical issues and clinical outcomes after postoperative volumetric-modulated arc therapy (VMAT) in two cases of malignant lacrimal gland cancer.
Patients & methods: Patients were treated by postoperative VMAT and post-treatment clinical outcomes were followed-up to 18 months.
Results: Dosimetric results were acceptable and acute toxicity was manageable in both patients. No evidence of disease was found at latest follow-up. One patient underwent corneal transplant for central corneal ulceration, experiencing reduction of visual acuity.
Conclusion: Postoperative VMAT for treatment of lacrimal gland tumors offers improved outcome, with manageable side effects. In the context of photon beam radiotherapy, VMAT emerged as a valuable treatment option for these malignant tumors.
Keywords: VMAT; adenoid cystic carcinoma; carcinoma ex pleomorphic adenoma; dosimetric evaluation; lacrimal gland tumor; postoperative intensity-modulated radiation therapy; treatment planning.