Past experience resets behavior: CaMK takes the heat

Swathi Yadlapalli; Khursheed A Wani; X Z Shawn Xu

doi:10.1016/j.neuron.2014.11.014

Past experience resets behavior: CaMK takes the heat

Neuron. 2014 Dec 3;84(5):883-5. doi: 10.1016/j.neuron.2014.11.014.

Authors

Swathi Yadlapalli¹, Khursheed A Wani¹, X Z Shawn Xu²

Affiliations

¹ Life Sciences Institute and Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
² Life Sciences Institute and Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: shawnxu@umich.edu.

Abstract

How past experiences reshape behavior is not well understood. In this issue, two studies (Schild et al., 2014; Yu et al., 2014) dissected the molecular mechanisms underlying experience-dependent plasticity in thermosensory behavior. They show that Ca(2+)/calmodulin-dependent kinase I (CaMKI) regulates thermal preferences according to past experience.

Abstract

Grant support