ICMA: an integrated cardiac modeling and analysis platform

Bioinformatics. 2015 Apr 15;31(8):1331-3. doi: 10.1093/bioinformatics/btu809. Epub 2014 Dec 6.


ICMA, a software framework to create 3D finite element models of the left ventricle from cardiac ultrasound or magnetic resonance imaging (MRI) data, has been made available as an open-source code. The framework is hardware vendor independent and uses speckle tracking (endocardial border detection) on ultrasound (MRI) imaging data in the form of DICOM. Standard American Heart Association segment-based strain analysis can be performed using a browser-based interface. The speckle tracking, border detection and model fitting methods are implemented in C++ using open-source tools. They are wrapped as web services and orchestrated via a JBOSS-based application server.

Availability and implementation: The source code for ICMA is freely available under MPL 1.1 or GPL 2.0 or LGPL 2.1 license at https://github.com/ABI-Software-Laboratory/ICMA and a standalone virtual machine at http://goo.gl/M4lJKH for download.

Contact: r.jagir@auckland.ac.nz

Supplementary information: Supplementary materials are available at Bioinformatics online.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / methods*
  • Databases, Factual
  • Diagnostic Imaging*
  • Heart / anatomy & histology*
  • Heart Ventricles / anatomy & histology*
  • Humans
  • Models, Cardiovascular*
  • Software*