Full-wave intravascular ultrasound simulation from histology

Med Image Comput Comput Assist Interv. 2014;17(Pt 2):627-34. doi: 10.1007/978-3-319-10470-6_78.


In this paper, we introduce a framework for simulating intravascular ultrasound (IVUS) images and radiofrequency (RF) signals from histology image counterparts. We modeled the wave propagation through the Westervelt equation, which is solved explicitly with a finite differences scheme in polar coordinates by taking into account attenuation and non-linear effects. Our results demonstrate good correlation for textural and spectral information driven from simulated IVUS data in contrast to real data, acquired with single-element mechanically rotating 40 MHZ transducer, as ground truth.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Equipment Design
  • Equipment Failure Analysis
  • Image Interpretation, Computer-Assisted / instrumentation*
  • Image Interpretation, Computer-Assisted / methods*
  • Microscopy / instrumentation*
  • Microscopy / methods*
  • Phantoms, Imaging*
  • Radio Waves
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Ultrasonography, Interventional / instrumentation*
  • Ultrasonography, Interventional / methods*