First-in-man radial access renal denervation with the ReCor Radiance™ catheter

EuroIntervention. 2015 Feb;10(10):1209-12. doi: 10.4244/EIJY14M12_03.


Aims: Renal denervation is a potential new treatment therapy for resistant hypertension. However, anatomic vascular variations might complicate the procedure and increase complications. A radial approach offers easier renal artery access and is associated with a decreased risk of vascular access complications.

Methods and results: We describe the first-in-man use of a radial access ultrasound-based renal denervation device (Radiance™; ReCor, Palo Alto, CA, USA) in two patients with therapy-resistant hypertension. Both procedures were uneventful and resulted in significant blood pressure reductions at three-month follow-up (mean office blood pressure drop [-40/-29 mmHg]; mean ambulatory blood pressure drop [-11/-8 mmHg]).

Conclusions: Radial access renal artery denervation using the Radiance catheter appears to be safe and effective and should be considered an alternative option in patients referred for renal denervation.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Aged
  • Catheter Ablation / instrumentation*
  • Catheter Ablation / methods
  • Humans
  • Hypertension / surgery*
  • Male
  • Middle Aged
  • Piezosurgery / instrumentation*
  • Piezosurgery / methods
  • Radial Artery*
  • Renal Artery / innervation
  • Renal Artery / surgery*
  • Sympathectomy / instrumentation*
  • Sympathectomy / methods
  • Vascular Access Devices