Potential drug interaction between Rho(D) immune globulin and live virus vaccine

Nurs Womens Health. 2014 Dec;18(6):519-22. doi: 10.1111/1751-486X.12165.


Women often receive Rho(D) immune globulin as well as a live virus vaccine in the immediate postpartum period. The immune globulin product has the potential to interfere with appropriate immune response to the vaccine. Here we describe our approach to identifying and following up on this often overlooked potential drug interaction.

Keywords: MMR; Rho(D) immune globulin; postpartum vaccination; varicella vaccine.

MeSH terms

  • Drug Interactions*
  • Female
  • Humans
  • Measles-Mumps-Rubella Vaccine / adverse effects*
  • Measles-Mumps-Rubella Vaccine / therapeutic use
  • Rho(D) Immune Globulin / adverse effects*
  • Rho(D) Immune Globulin / therapeutic use


  • Measles-Mumps-Rubella Vaccine
  • Rho(D) Immune Globulin