Contemporary indications for transsphenoidal pituitary surgery

Brandon A Miller; Adriana G Ioachimescu; Nelson M Oyesiku

doi:10.1016/j.wneu.2014.07.037

Contemporary indications for transsphenoidal pituitary surgery

World Neurosurg. 2014 Dec;82(6 Suppl):S147-51. doi: 10.1016/j.wneu.2014.07.037.

Authors

Brandon A Miller¹, Adriana G Ioachimescu¹, Nelson M Oyesiku²

Affiliations

¹ Department of Neurosurgery, Emory University, Atlanta, Georgia, USA.
² Department of Neurosurgery, Emory University, Atlanta, Georgia, USA. Electronic address: noyesik@emory.edu.

PMID: 25496626
DOI: 10.1016/j.wneu.2014.07.037

Abstract

Objective: To analyze current indications for transsphenoidal pituitary surgery.

Methods: The current literature regarding transsphenoidal surgery for all subtypes of pituitary adenomas and other sellar lesions was examined. Alternate approaches for pituitary surgery were also reviewed.

Results: Transsphenoidal surgery continues to be the mainstay of surgical treatment for pituitary tumors, and has good outcomes in experienced hands. Pre- and postoperative management of pituitary tumors remains an important part of the treatment of patients with pituitary tumors.

Conclusions: Even as medical and surgical treatment for pituitary tumors evolves, transsphenoidal surgery remains a mainstay of treatment. Outcomes after transshenoidal surgery have improved over time. Neurosurgeons must be aware of the indications, risks and alternatives to transsphenoidal pituitary surgery.

Keywords: Pituitary adenoma; Pituitary surgery.

Publication types

Review

MeSH terms

Endoscopy / methods*
Humans
Neurosurgical Procedures / methods*
Pituitary Diseases / surgery*
Pituitary Gland / surgery*
Pituitary Neoplasms / surgery*
Postoperative Care
Sphenoid Bone / surgery*