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. 2015 Apr;206(4):339-40.
doi: 10.1192/bjp.bp.114.151316. Epub 2014 Dec 11.

Right superior temporal gyrus volume in adolescents with a history of suicide attempt

Lisa A Pan  1 , Lisa Ramos  1 , AnnaMaria Segreti  1 , David A Brent  1 , Mary L Phillips  1
Affiliations

Right superior temporal gyrus volume in adolescents with a history of suicide attempt

Lisa A Pan et al. Br J Psychiatry. 2015 Apr.

Abstract

The extent to which observed differences in emotion processing and regulation neural circuitry in adolescents with a history of suicide attempt are paralleled by structural differences is unknown. We measured brain cortical thickness and grey- and white-matter volumes in 100 adolescents: 28 with a history of suicide attempt and major depressive disorder (MDD); 31 with a history of MDD but no suicide attempt; and a healthy control group (n = 41). The first group compared with controls showed reduction in grey-matter volume in the right superior temporal gyrus (BA38), a region important for social emotion processing.

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Conflict of interest statement

Declaration of interest

None.

Figures

Fig. 1
Fig. 1
Diminished cortical volume in the right superior temporal gyrus in adolescents with a history of suicide attempt compared with a healthy control group (Brodmann area BA38, x = 35, y = 13, z = -41, vertex = 160, cluster size 889.80 mm2; P<0.05 corrected) with cortical volume post hoc t-tests, study group, covarying for age, gender, difference in scanners and total brain volume.
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