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. 2015 Feb;103(2):382-7.e2.
doi: 10.1016/j.fertnstert.2014.10.039. Epub 2014 Dec 10.

Birth Weight Is Associated With Inner Cell Mass Grade of Blastocysts

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Birth Weight Is Associated With Inner Cell Mass Grade of Blastocysts

Frederick Licciardi et al. Fertil Steril. .

Abstract

Objective: To determine the relationship between blastocyst growth parameters and birth weight.

Design: Cohort study.

Setting: University-affiliated fertility center.

Patient(s): In vitro patients who delivered a singleton after a single-blastocyst transfer.

Intervention(s): None.

Main outcome measure(s): Birth weight adjusted for gestational age at delivery and gender, with adjusted birth weight examined for association with blastocyst scores and grades.

Result(s): After standard in vitro fertilization (IVF) and thawed embryo transfers, greater birth weight was associated with a higher inner cell mass grade. The grade of the trophectoderm and stage of the blastocyst did not relate to weight.

Conclusion(s): Embryonic growth as early as day 5 can predict the progress of fetal development as measured by birth weight.

Keywords: Birth weight; blastocyst grades; in vitro fertilization.

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