Solitary liver lesions in children: interobserver agreement and accuracy of MRI diagnosis

Clin Imaging. May-Jun 2015;39(3):442-8. doi: 10.1016/j.clinimag.2014.11.014. Epub 2014 Nov 22.


Purpose: The purpose of the study was to evaluate interobserver agreement (IOA) and accuracy of magnetic resonance imaging (MRI) diagnosis of pediatric solitary liver lesions (PSLLs).

Methods: Fifty consecutive MRIs performed for PSLLs were reviewed to assess IOA and agreement between consensus imaging diagnosis and final diagnosis indicating accuracy using kappa statistics.

Results: In 39/50 cases, the MRI diagnosis given by two readers matched with substantial IOA (kappa=0.7294). There was moderate agreement (kappa=0.60784) between consensus imaging diagnosis and the final diagnosis in 10 cases with available pathology.

Conclusion: Based on the limited available pathology and follow-up, we found that most PSLLs can be noninvasively characterized and accurately diagnosed using MRI.

Keywords: Children; Interobserver agreement; MRI; Solitary liver lesions.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Liver / pathology*
  • Liver Neoplasms / diagnosis*
  • Magnetic Resonance Imaging / methods
  • Magnetic Resonance Imaging / standards*
  • Male
  • Observer Variation
  • Reproducibility of Results
  • Retrospective Studies