The doctor's dilemma: challenges in the diagnosis and care of homozygous familial hypercholesterolemia

J Clin Lipidol. 2014 Nov-Dec;8(6):542-549. doi: 10.1016/j.jacl.2014.09.005. Epub 2014 Sep 19.

Authors

Seth J Baum¹, E J G Sijbrands², Pedro Mata³, Gerald F Watts⁴

Affiliations

¹ University of Miami Miller School of Medicine, Miami, Florida. Electronic address: sjbaum@fpim.org.
² Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
³ Fundacion Hipercolesterolemia Familiar, Madrid, Spain.
⁴ Lipid Disorders Clinic, Cardiovascular Medicine, Royal Perth Hospital School of Medicine and Pharmacology, University of Western Australia, Australia.

PMID: 25499935
DOI: 10.1016/j.jacl.2014.09.005

No abstract available

Publication types

Editorial

MeSH terms

Algorithms
Atherosclerosis / diagnosis*
Atherosclerosis / drug therapy
Atherosclerosis / etiology
Benzimidazoles / therapeutic use
Consanguinity
Diagnosis, Differential
Genetic Testing
Homozygote
Humans
Hyperlipoproteinemia Type II / complications
Hyperlipoproteinemia Type II / diagnosis*
Hyperlipoproteinemia Type II / drug therapy
Lipid Metabolism / drug effects
Lipid Metabolism / genetics
Mutation / genetics
Oligonucleotides / therapeutic use
Practice Guidelines as Topic
Receptors, LDL / genetics*

Substances

BMS201038
Benzimidazoles
Oligonucleotides
Receptors, LDL
mipomersen