[Changes in the levels of ACTH and cortisol after passive exposure to cigarette smoke in smokers and non-smokers]

Boll Soc Ital Biol Sper. 1989 Apr;65(4):365-9.
[Article in Italian]


Plasma ACTH and cortisol levels were studied in smokers and non smokers, (exposed or not to smoke of the environment), after passive exposure to cigarette smoking. Non smokers, usually not exposed to smoke, show a rise in both hormones, whereas smokers and non smokers commonly exposed to smoke don't show any change in ACTH and cortisol levels. These data suggest that nicotine acts as an acute stimulus on the hypophysis-adrenal axis even passively inhaled.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adrenocorticotropic Hormone / blood*
  • Adult
  • Humans
  • Hydrocortisone / blood*
  • Hypothalamo-Hypophyseal System / drug effects
  • Nicotine / pharmacology
  • Pituitary-Adrenal System / drug effects
  • Smoking / blood*
  • Tobacco Smoke Pollution*


  • Tobacco Smoke Pollution
  • Nicotine
  • Adrenocorticotropic Hormone
  • Hydrocortisone