Polycystic kidney disease. HALTing PKD progression--revival of blood pressure control

Nat Rev Nephrol. 2015 Mar;11(3):129-31. doi: 10.1038/nrneph.2014.241. Epub 2014 Dec 16.


New research suggests that rigorous blood pressure control is beneficial in early autosomal dominant polycystic kidney disease (ADPKD). Although a positive effect on the rate of decline of estimated glomerular filtration rate remains to be demonstrated, this study is likely to change current treatment strategies for young patients with ADPKD.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Antihypertensive Agents / therapeutic use*
  • Benzimidazoles / therapeutic use*
  • Benzoates / therapeutic use*
  • Female
  • Humans
  • Hypertension / drug therapy*
  • Kidney / pathology*
  • Lisinopril / therapeutic use*
  • Male
  • Polycystic Kidney, Autosomal Dominant / drug therapy*


  • Antihypertensive Agents
  • Benzimidazoles
  • Benzoates
  • Lisinopril