Air contamination in the sclerosing foam for the treatment of varicose veins

Phlebology. 2016 Mar;31(2):96-100. doi: 10.1177/0268355514565194. Epub 2014 Dec 15.

Abstract

Background: Fluids and drugs formulated for intravenous infusion may potentially promote the growth of microorganisms that can cause infections. The aim of this study is to test the sterility of sclerosing foam.

Methods: Polidocanol was used for the production of the foam. The Tessari method was used in order to generate the foam. The preparation was carried out both in the operating theater and in an outpatient room. A validation test with microorganisms was also performed.

Results: The measurements showed no evident growth of microorganisms and in the validation tests the foam appeared to even display bacteriostatic and/or bactericide properties.

Conclusions: Sclerosing foam seems to be safe from a microbiological point of view.

Keywords: Chronic venous disease; foam sclerotherapy; infectious disease; sclerotherapy; varicose veins.

MeSH terms

  • Air Microbiology*
  • Air*
  • Drug Contamination / prevention & control*
  • Female
  • Humans
  • Male
  • Polidocanol
  • Polyethylene Glycols / administration & dosage*
  • Sclerosing Solutions*
  • Varicose Veins / surgery*

Substances

  • Sclerosing Solutions
  • Polidocanol
  • Polyethylene Glycols