doi: 10.1016/j.stem.2014.10.012.
Epub 2014 Nov 6.
Stem cells to insulin secreting cells: two steps forward and now a time to pause?
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- PMID: 25517460
- DOI: 10.1016/j.stem.2014.10.012
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Stem cells to insulin secreting cells: two steps forward and now a time to pause?
Cell Stem Cell.
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Free article
Abstract
Two groups recently reported the in vitro differentiation of human embryonic stem cells into insulin-secreting cells, achieving an elusive goal for regenerative medicine. Herein we provide a perspective regarding these developments, compare phenotypes of the insulin-containing cells to human β cells, and discuss implications for type 1 diabetes research and clinical care.
Copyright © 2014 Elsevier Inc. All rights reserved.
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