Perhydroxylcucurbit[6]uril as a highly selective gas chromatographic stationary phase for analytes of wide-ranging polarity

J Sep Sci. 2015 Mar;38(5):821-4. doi: 10.1002/jssc.201400876. Epub 2015 Jan 19.


This work describes the separation performance of a perhydroxylcucurbit[6]uril stationary phase for capillary gas chromatography. The perhydroxylcucurbit[6]uril stationary phase exhibits higher resolving capabilities for critical analytes with better peak shapes than cucurbit[6]uril and conventional stationary phases. The advantageous separation feature of the perhydroxylcucurbit[6]uril stationary phase may originate from its unique structure and favorably balanced interactions with the analytes. Also, the perhydroxylcucurbit[6]uril column shows good separation repeatability with relative standard deviations in the range of 0.01-0.13% for intraday, 0.37-0.82% for interday, and 1.0-4.7% for column-to-column repeatability.

Keywords: Capillary gas chromatography; Cucurbit[6]uril; Perhydroxylcucurbit[6]uril; Stationary phases.