The diagnostic value of technetium 99m pertechnetate salivary gland scintigraphy in patients with certain salivary gland diseases

J Oral Maxillofac Surg. 2015 Mar;73(3):443-50. doi: 10.1016/j.joms.2014.09.013. Epub 2014 Oct 2.

Abstract

Purpose: To evaluate the diagnostic value of technetium 99m pertechnetate salivary gland scintigraphy in patients with certain salivary gland diseases.

Materials and methods: We evaluated 47 patients: 25 with chronic obstructive parotitis, 12 with sialolithiasis, and 10 with Sjögren syndrome. All of the patients underwent preoperative (99m)Tc-pertechnetate salivary gland scintigraphy. Patients with chronic obstructive parotitis also underwent ultrasonography, sialography, and sialoendoscopy; patients with sialolithiasis also underwent ultrasonography and computed tomography; and patients with Sjögren syndrome also underwent ultrasonography and sialography. We made comparisons between (99m)Tc-pertechnetate salivary gland scintigraphy and the other aforementioned diagnostic tests to investigate the role of (99m)Tc-pertechnetate salivary gland scintigraphy in diseases of the salivary glands.

Results: In patients with chronic obstructive parotitis, (99m)Tc-pertechnetate salivary gland scintigraphy showed reduced excretion by the affected glands, whereas uptake was nearly normal. Among patients with sialolithiasis, (99m)Tc-pertechnetate salivary gland scintigraphy showed reduced excretion by the affected glands and decreased uptake in 5 patients. In patients with Sjögren syndrome, (99m)Tc-pertechnetate salivary gland scintigraphy showed a decrease in both excretion and uptake by the 4 glands.

Conclusions: Technetium 99m pertechnetate salivary gland scintigraphy played a substantial role in the diagnosis and differential diagnosis of salivary gland diseases.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Chronic Disease
  • Diagnosis, Differential
  • Dilatation / methods
  • Endoscopy / methods
  • Humans
  • Middle Aged
  • Parotitis / diagnostic imaging
  • Radionuclide Imaging
  • Radiopharmaceuticals*
  • Salivary Ducts / diagnostic imaging
  • Salivary Gland Calculi / diagnostic imaging
  • Salivary Gland Diseases / diagnostic imaging*
  • Salivary Glands / diagnostic imaging*
  • Sialography / methods
  • Sjogren's Syndrome / diagnostic imaging
  • Sodium Pertechnetate Tc 99m*
  • Therapeutic Irrigation / methods
  • Tomography, X-Ray Computed / methods
  • Ultrasonography
  • Young Adult

Substances

  • Radiopharmaceuticals
  • Sodium Pertechnetate Tc 99m