Abstract
Two new dammaranes, dysomollisol (1) and dysomollisone (2), along with seven known compounds (3-9) were isolated and identified from the fruits of Dysoxylum mollissimum. The structures of these compounds were determined on the basis of spectroscopic analyses, including 1D and 2D NMR, UV, IR and mass spectrometry. The antibacterial activity and cytotoxicity against epidermoid carcinoma of oral cavity (KB) cell line of compounds 1-9 were evaluated.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents / chemistry
-
Anti-Bacterial Agents / pharmacology
-
Antineoplastic Agents / chemistry
-
Antineoplastic Agents / pharmacology
-
Cell Line, Tumor
-
Cell Survival / drug effects
-
Dammaranes
-
Fruit / chemistry*
-
Humans
-
Magnetic Resonance Spectroscopy
-
Meliaceae / chemistry*
-
Molecular Structure
-
Terpenes / chemistry*
-
Terpenes / pharmacology
-
Triterpenes / chemistry*
-
Triterpenes / pharmacology
Substances
-
Anti-Bacterial Agents
-
Antineoplastic Agents
-
Terpenes
-
Triterpenes