A race for an Ebola vaccine: promises and obstacles

Trends Microbiol. 2015 Feb;23(2):65-6. doi: 10.1016/j.tim.2014.12.005. Epub 2014 Dec 17.

Abstract

While several impeding factors have limited Ebola vaccine development, the current epidemic has provided a surge which may lead to a record pace for a vaccine against Ebola. Consequently, multiple FDA trials are currently underway using two promising vaccine platforms; one has recently demonstrated durable immunity within non-human primates.

Keywords: Ebola; FDA clinical trial; durable immunity; immune correlates; vaccine.

MeSH terms

  • Animals
  • Ebola Vaccines* / immunology
  • Ebola Vaccines* / therapeutic use
  • Hemorrhagic Fever, Ebola / prevention & control*
  • Humans
  • Primates

Substances

  • Ebola Vaccines