The lack of consensus in management of malignant struma ovarii

Gynecol Endocrinol. 2015 Apr;31(4):258-9. doi: 10.3109/09513590.2014.995616. Epub 2014 Dec 24.

Abstract

Struma ovarii is a rare variant of teratoma characterized by the presence of thyroid tissue in more than 50%. Malignant transformation is rare (less than 5%) and the criteria to classify this condition have changed over time. Nowadays it must fulfill the histological categories of differentiated thyroid carcinoma. Its treatment is controversial and there is no unanimous management. We present three cases of women with malignant struma ovarii, diagnosed by the surgical specimen.

Keywords: Management; struma ovarii; thyroid.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma / diagnosis
  • Carcinoma / pathology
  • Carcinoma / radiotherapy
  • Carcinoma / surgery
  • Combined Modality Therapy
  • Consensus
  • Diagnosis, Differential
  • Female
  • Humans
  • Iodine Radioisotopes / therapeutic use
  • Middle Aged
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / radiotherapy
  • Ovarian Neoplasms / surgery*
  • Ovariectomy*
  • Precision Medicine*
  • Radiopharmaceuticals / therapeutic use
  • Struma Ovarii / diagnosis
  • Struma Ovarii / pathology
  • Struma Ovarii / radiotherapy
  • Struma Ovarii / surgery*
  • Thyroid Neoplasms / diagnosis
  • Thyroid Neoplasms / pathology
  • Thyroid Neoplasms / radiotherapy
  • Thyroid Neoplasms / surgery
  • Thyroidectomy
  • Treatment Outcome

Substances

  • Iodine Radioisotopes
  • Radiopharmaceuticals