Danish Rural Eye Study: the association of preschool vision screening with the prevalence of amblyopia

Acta Ophthalmol. 2015 Jun;93(4):322-9. doi: 10.1111/aos.12639. Epub 2014 Dec 28.

Abstract

Purpose: To determine the prevalence of amblyopia in Denmark before and after the initiation of the Danish national preschool vision screening programme.

Methods: In a population-based cross-sectional study, 3826 participants of the Danish General Suburban Population Study (GESUS) aged 20 years and older from a Danish rural municipality received a complete general health examination and an ophthalmological interview and examination. This study included a comprehensive ophthalmologic interview, measurement of best corrected visual acuity (BCVA) in each eye, Hirschberg's test for strabismus and two 45-degree retinal fundus photographs of each eye. A complete ophthalmologic examination was performed when indicated.

Results: The prevalence of monocular visual impairment (MVI) was 4.26% (95% CI, 3.66-4.95, n = 163). Amblyopia was the most common cause, accounting for 33%. The prevalence of amblyopia was 1.44% (95% CI, 1.01-1.81, n = 55), being higher among non-preschool vision screened persons compared to those who were offered (estimated 95% attendance) preschool vision screening (1.78%, n = 41, 95% CI 1.24-2.33 versus 0.44%, n = 2, 95% CI, 0.12-1.60, p = 0.024). The leading cause of amblyopia was anisometropia (45.5%, 25/55).

Conclusions: Amblyopia was the most common cause of MVI. Following the initiation of the Danish national preschool vision screening programme, which has an approximate attendance rate of 95%, the prevalence of amblyopia decreased by fourfold.

Keywords: amblyopia; childhood vision screening; population-based; prevalence.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Amblyopia / epidemiology*
  • Cross-Sectional Studies
  • Denmark / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Persons with Visual Disabilities / statistics & numerical data*
  • Prevalence
  • Rural Population / statistics & numerical data*
  • Vision Screening*
  • Visual Acuity / physiology
  • Young Adult