Attentional flexibility in the thalamus: now we're getting SOMwhere

Nat Neurosci. 2015 Jan;18(1):2-4. doi: 10.1038/nn.3902.

Abstract

Loss of the receptor tyrosine kinase ErbB4 in somatostatin (SOM) inhibitory neurons of the thalamic reticular nucleus (TRN) enhances top-down cortical feedback, improving feature detection at the cost of reduced ability to switch attention. The study furthers our understanding of the circuit mechanisms underlying TRN function.

Publication types

  • News
  • Comment

MeSH terms

  • Animals
  • Male
  • Receptor, ErbB-4 / physiology*
  • Sensation / physiology*
  • Sensory Gating / physiology*
  • Thalamic Nuclei / physiology*

Substances

  • Erbb4 protein, mouse
  • Receptor, ErbB-4