Cell death machinery makes life more robust

Elife. 2014 Dec 30;3:e05816. doi: 10.7554/eLife.05816.

Abstract

CED-3, a protein that is essential for programmed cell death, also has an unexpected role in the regulation of non-apoptotic genes during normal development.

Keywords: C. elegans; DIS3L2; LIN28; caspase; development; developmental biology; heterochronic; miRNA; stem cells.

Publication types

  • Comment

MeSH terms

  • Animals
  • Apoptosis / genetics*
  • Caenorhabditis elegans / embryology*
  • Caenorhabditis elegans / genetics*
  • Caenorhabditis elegans Proteins / metabolism*
  • Caspases / metabolism*
  • Embryonic Development / genetics*
  • Gene Expression Regulation, Developmental*
  • Humans
  • MicroRNAs / metabolism*

Substances

  • Caenorhabditis elegans Proteins
  • MicroRNAs
  • Caspases