Costs of eliminating malaria and the impact of the global fund in 34 countries

PLoS One. 2014 Dec 31;9(12):e115714. doi: 10.1371/journal.pone.0115714. eCollection 2014.


Background: International financing for malaria increased more than 18-fold between 2000 and 2011; the largest source came from The Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund). Countries have made substantial progress, but achieving elimination requires sustained finances to interrupt transmission and prevent reintroduction. Since 2011, global financing for malaria has declined, fueling concerns that further progress will be impeded, especially for current malaria-eliminating countries that may face resurgent malaria if programs are disrupted.

Objectives: This study aims to 1) assess past total and Global Fund funding to the 34 current malaria-eliminating countries, and 2) estimate their future funding needs to achieve malaria elimination and prevent reintroduction through 2030.

Methods: Historical funding is assessed against trends in country-level malaria annual parasite incidences (APIs) and income per capita. Following Kizewski et al. (2007), program costs to eliminate malaria and prevent reintroduction through 2030 are estimated using a deterministic model. The cost parameters are tailored to a package of interventions aimed at malaria elimination and prevention of reintroduction.

Results: The majority of Global Fund-supported countries experiencing increases in total funding from 2005 to 2010 coincided with reductions in malaria APIs and also overall GNI per capita average annual growth. The total amount of projected funding needed for the current malaria-eliminating countries to achieve elimination and prevent reintroduction through 2030 is approximately US$8.5 billion, or about $1.84 per person at risk per year (PPY) (ranging from $2.51 PPY in 2014 to $1.43 PPY in 2030).

Conclusions: Although external donor funding, particularly from the Global Fund, has been key for many malaria-eliminating countries, sustained and sufficient financing is critical for furthering global malaria elimination. Projected cost estimates for elimination provide policymakers with an indication of the level of financial resources that should be mobilized to achieve malaria elimination goals.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Financing, Organized / economics
  • Health Services Needs and Demand / economics*
  • Humans
  • International Cooperation*
  • Malaria / economics*
  • Malaria / prevention & control*
  • Needs Assessment

Grants and funding

The University of California San Francisco Global Health Group's Malaria Elimination Initiative is supported by grants from the Bill & Melinda Gates Foundation. The authors declare that no funding bodies had any role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.