Co-circulation of dengue virus type 3 genotypes in Vientiane capital, Lao PDR

Malayvanh Lao; Valérie Caro; Jean-Michel Thiberge; Phaitong Bounmany; Khamsing Vongpayloth; Philippe Buchy; Veasna Duong; Chansamone Vanhlasy; Jean-Marie Hospied; Manichanh Thongsna; Khamla Choumlivong; Phonesavanh Vongkhamchanh; Bounleua Oudavong; Paul T Brey; Marc Grandadam

doi:10.1371/journal.pone.0115569

Co-circulation of dengue virus type 3 genotypes in Vientiane capital, Lao PDR

PLoS One. 2014 Dec 31;9(12):e115569. doi: 10.1371/journal.pone.0115569. eCollection 2014.

Authors

Affiliations

¹ Institut Pasteur du Laos, Vientiane, Lao PDR.
² Institut Pasteur, Paris, France.
³ Institut Pasteur du Cambodge, Phnom Penh, Cambodia.
⁴ Military Hospital 103, Vientiane, Lao PDR.
⁵ Centre Medical de l'ambassade de France, Vientiane, Lao PDR.
⁶ Mittaphab Hospital, Vientiane, Lao PDR.
⁷ Setthathirath Hospital, Vientiane, Lao PDR.
⁸ 5 April Police Hospital, Vientiane, Lao PDR.
⁹ Children Hospital, Vientiane, Lao PDR.

Abstract

During the 2012 epidemic of dengue in Vientiane capital, Lao PDR, a major serotype switch from dengue 1 to 3 was observed. A molecular epidemiology study demonstrated that dengue 3 remained the predominant serotype in 2013, but also revealed the co-circulation of two genotypes, supporting the hypothesis of multiple geographic origins of dengue 3 strains circulating in Vientiane capital.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Child
Child, Preschool
Dengue / epidemiology*
Dengue Virus / classification
Dengue Virus / genetics*
Dengue Virus / isolation & purification
Dengue Virus / physiology
Epidemiological Monitoring
Female
Genotype*
Humans
Laos / epidemiology
Male
Middle Aged
Molecular Epidemiology
Phylogeny
Serogroup
Young Adult