Co-circulation of dengue virus type 3 genotypes in Vientiane capital, Lao PDR

PLoS One. 2014 Dec 31;9(12):e115569. doi: 10.1371/journal.pone.0115569. eCollection 2014.

Abstract

During the 2012 epidemic of dengue in Vientiane capital, Lao PDR, a major serotype switch from dengue 1 to 3 was observed. A molecular epidemiology study demonstrated that dengue 3 remained the predominant serotype in 2013, but also revealed the co-circulation of two genotypes, supporting the hypothesis of multiple geographic origins of dengue 3 strains circulating in Vientiane capital.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Dengue / epidemiology*
  • Dengue Virus / classification
  • Dengue Virus / genetics*
  • Dengue Virus / isolation & purification
  • Dengue Virus / physiology
  • Epidemiological Monitoring
  • Female
  • Genotype*
  • Humans
  • Laos / epidemiology
  • Male
  • Middle Aged
  • Molecular Epidemiology
  • Phylogeny
  • Serogroup
  • Young Adult

Grant support

This work was supported by the Institut Pasteur's International Division (ACIP 2016-16). Diagnosis and surveillance activities benefitted the support of Institut Pasteur's International Division (Emergency fund) and donations from AusAID/WHO; ST Bank; Phongsavanh Bank; Exotissimo travel Co.,ltd; Lao Brewery Co., LTD; Phu Bai Mining limited; and the Banque Franco-Lao ltd. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.