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Case Reports
, 35 (1), 137-40

ABO*Ael03/O Genotype With ABO Discrepancy: The First Case in Korea

Case Reports

ABO*Ael03/O Genotype With ABO Discrepancy: The First Case in Korea

Bo Kyeung Jung et al. Ann Lab Med.


The Ael subgroup expresses the least amount of A antigens and could only be detected by performing the adsorption-elution test. The frequency of the Ael subgroup is about 0.001% in Koreans, and the Ael02 allele, which originates from A102, is the most frequently identified allele in the Korean population. We report a Korean family with the Ael03 allele identified by molecular genetic analysis. To the best of our knowledge, this is the first such report in Korea to date.

Keywords: ABO subgroup; Ael; Ael03.

Conflict of interest statement

No potential conflicts of interest relevant to this article were reported.


Fig. 1
Fig. 1
The pedigree and the results of sequencing. (A) Pedigree demonstrating the inheritance of the Ael03 allele. The phenotype and genotype are indicated below each symbol. The arrow indicates proband. (B) Schemes for generation of frame shift mutation caused by single-base deletion at nucleotide 804.

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