The effect of intra-articular Tenoxicam on knee effusion after arthroscopy

Int Orthop. 2015 Jul;39(7):1423-6. doi: 10.1007/s00264-014-2640-3. Epub 2015 Jan 6.

Abstract

Purpose: NSAIDs and analgesic drugs are used intra-articularly after knee arthroscopy for pain relief. However, synovial effusion is still a common cause of delayed physical therapy. The aim of this study was to demonstrate the beneficial effect of intra-articular injection of Tenoxicam on knee effusion after arthroscopy.

Method: This was a prospective non-randomized study on 134 patients with a mean age of 36.7 years. Knee arthroscopy on a day-case basis was performed; normal saline was used for irrigation. At the end of the procedure, fluid was aspirated from the knee joint and 20 ml of Tenoxicam diluted with 20 ml of 0.9% normal saline was injected into the knee five minutes before deflation of limb tourniquet. The same surgeon performed clinical examination for knee effusion 14 days postoperatively.

Results: Encountered pathologies included meniscal injury, degenerative arthropathy, synovial plica and ACL rupture. Knee effusion developed in 15.7% of the patients, particularly in those with degenerative arthropathy (p = 0.006) and meniscal lesions (p = 0.06).

Conclusion: Intra-articular Tenoxicam is a simple method for the prevention of postoperative knee effusion. Degenerative arthropathy and meniscal lesions are major risk factors for post arthroscopy knee effusion.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Analgesics / therapeutic use
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Arthroscopy* / adverse effects
  • Child
  • Female
  • Humans
  • Injections, Intra-Articular
  • Male
  • Middle Aged
  • Pain Measurement
  • Pain, Postoperative / prevention & control
  • Piroxicam / administration & dosage
  • Piroxicam / analogs & derivatives*
  • Piroxicam / pharmacology
  • Piroxicam / therapeutic use
  • Prospective Studies
  • Synovial Fluid / drug effects*
  • Tourniquets
  • Young Adult

Substances

  • Analgesics
  • Anti-Inflammatory Agents, Non-Steroidal
  • Piroxicam
  • tenoxicam