Nervous system manifestations of Lyme disease

Rheum Dis Clin North Am. 1989 Nov;15(4):635-47.


Neurologic involvement is commonplace in Lyme borreliosis. Neuropathies can be acute or chronic, focal or disseminated, but are predominantly axonal. CNS infection can also be acute or indolent, focal or disseminated; meningitis, encephalitis, and cranial nerve palsies occur. A mild encephalopathy is also common, but only occasionally due to CNS infection.

Publication types

  • Review

MeSH terms

  • Central Nervous System Diseases / diagnosis*
  • Cranial Nerve Diseases / diagnosis
  • Diagnosis, Differential
  • Humans
  • Lyme Disease / diagnosis*
  • Peripheral Nervous System Diseases / diagnosis*