Chronic opioid pain management for chronic kidney disease

J Pain Palliat Care Pharmacother. 2015 Mar;29(1):48-50. doi: 10.3109/15360288.2014.997850. Epub 2015 Jan 5.


Questions from patients about pain conditions, pain treatment, and responses from authors are presented to help educate patients and make them effective self-advocates. The topics addressed in this issue are renal or kidney failure and chronic pain management with opioids, morphine, and oxycodone effect in the body over a period of time. This includes process of absorption, distribution, localization in tissues, biotransformation and excretion in chronic kidney disease, expected side effects and recommendations.

Keywords: chronic; dialysis; kidney disease; nephropathy; opioid.

MeSH terms

  • Analgesics, Opioid / adverse effects
  • Analgesics, Opioid / pharmacokinetics
  • Analgesics, Opioid / therapeutic use*
  • Chronic Pain / drug therapy*
  • Humans
  • Renal Insufficiency, Chronic / complications*
  • Renal Insufficiency, Chronic / therapy


  • Analgesics, Opioid