Disseminated histoplasmosis in a Danish patient with AIDS

Scand J Infect Dis. 1989;21(5):573-7. doi: 10.3109/00365548909037887.


We present the first case of disseminated histoplasmosis in an AIDS patient in Europe, a 33-year-old Danish homosexual man, and recommend a detailed travel history in HIV-positive patients presenting with fever, weight loss and organomegaly. In Scandinavia disseminated histoplasmosis is rare but should be kept in mind as the disease is a major opportunistic infection in patients with AIDS. Treatment with amphotericin B followed by fluconazole was effective.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Acquired Immunodeficiency Syndrome / immunology
  • Adult
  • Amphotericin B / therapeutic use
  • Denmark
  • Fluconazole / therapeutic use
  • Histiocytes / microbiology
  • Histoplasma / ultrastructure
  • Histoplasmosis / complications*
  • Histoplasmosis / drug therapy
  • Histoplasmosis / immunology
  • Homosexuality
  • Humans
  • Immunity, Cellular / immunology
  • Male
  • Microscopy, Electron


  • Amphotericin B
  • Fluconazole