No relationship between drug transporter genetic variants and tenofovir plasma concentrations or changes in glomerular filtration rate in HIV-infected adults

J Acquir Immune Defic Syndr. 2015 Apr 1;68(4):e56-9. doi: 10.1097/QAI.0000000000000504.
No abstract available

Publication types

  • Letter
  • Observational Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenine / adverse effects
  • Adenine / analogs & derivatives*
  • Adenine / pharmacokinetics
  • Adult
  • Anti-HIV Agents / adverse effects
  • Anti-HIV Agents / pharmacokinetics*
  • Cohort Studies
  • Female
  • Genotype
  • Glomerular Filtration Rate*
  • HIV Infections / drug therapy*
  • Humans
  • Male
  • Multidrug Resistance-Associated Proteins / genetics*
  • Organophosphonates / adverse effects
  • Organophosphonates / pharmacokinetics*
  • Plasma / chemistry*
  • Retrospective Studies
  • Tenofovir

Substances

  • ABCC4 protein, human
  • Anti-HIV Agents
  • Multidrug Resistance-Associated Proteins
  • Organophosphonates
  • multidrug resistance-associated protein 2
  • Tenofovir
  • Adenine