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Case Reports
. 2015 Jan 5;2015:bcr2014203776.
doi: 10.1136/bcr-2014-203776.

Histiocytic Necrotising Lymphadenitis (Kikuchi-Fujimoto Disease) of Axillary Lymph Nodes

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Free PMC article
Case Reports

Histiocytic Necrotising Lymphadenitis (Kikuchi-Fujimoto Disease) of Axillary Lymph Nodes

Santosh Nagaraju et al. BMJ Case Rep. .
Free PMC article

Abstract

Kikuchi-Fujimoto disease (KFD) or histiocytic necrotising lymphadenitis is a rare entity, occurring most commonly in young Asian adults. KFD is characterised by fever with tender lymph node enlargement. The cervical group of lymph nodes is most commonly involved, and the diagnosis is conclusively made by lymph node biopsy and histopathology. KFD is a self-limiting condition, which usually resolves over 1-4 months. Symptomatic treatment with antipyretics and/or non-steroidal anti-inflammatory drugs is recommended. Here we describe an uncommon presentation of KFD in a young woman in which only the axillary lymph nodes were enlarged.

Figures

Figure 1
Figure 1
Ultrasound image of left axilla, demonstrating enlarged hypoechoic lymph nodes.
Figure 2
Figure 2
H&E staining of left axillary lymph node biopsy (10× magnification), demonstrating effacement of lymph node (black arrows) and necrotic areas with histiocytic infiltration (yellow arrow).
Figure 3
Figure 3
H&E staining of left axillary lymph node biopsy (400× magnification), demonstrating necrotic areas with absence of neutrophilic infiltration.

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