Primary extrarenal Wilms' tumor in children

J Pediatr Surg. 1989 Dec;24(12):1283-8. doi: 10.1016/s0022-3468(89)80568-8.


We report three additional cases of primary extrarenal Wilms' tumor and review those cases previously documented. Analysis of the location, histopathology, treatment, and survival of these cases supports the following conclusions: Wilms' tumor may occur in an extrarenal location without primary renal involvement and must be included in the differential diagnosis of abdominal, pelvic, and inguinal masses; an extrarenal location supports a more frequent occurrence of ectopic metanephric blastema than was previously recognized or origin of Wilms' tumor from a more primitive mesodermal tissue; and the natural history and prognosis of extrarenal and renal Wilms' tumors appears similar.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Neoplasms / pathology
  • Adolescent
  • Child
  • Child, Preschool
  • Choristoma / pathology
  • Female
  • Humans
  • Infant
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / surgery
  • Male
  • Wilms Tumor / pathology*
  • Wilms Tumor / surgery