Serum insulin is significantly related to components of the metabolic syndrome in Japanese working women

Abstract

Background: The aim of this study was to examine the association between serum insulin levels and components of the metabolic syndrome (MetS) in working women.

Methods: The target subjects were 141 working women. Serum triglyceride, HDL cholesterol, uric acid, plasma insulin and plasma glucose were measured in addition to waist circumference and blood pressure.

Results: MetS was diagnosed based on the modified criteria of the International Diabetes Federation, and was present in 7.1% (10/141) of the study subjects. Stepwise multiple regression analysis showed that some components of MetS were significantly associated with log-transformed values of the serum insulin. The standardized regression coefficient for the waist circumference, high density lipoprotein cholesterol, systolic blood pressure and age were 0.238, -0.333, 0.309 and -0.156, respectively.

Conclusions: A statistically significant relationship existed between the components of MetS and the serum insulin levels in working women.