LINKPHASE3: an improved pedigree-based phasing algorithm robust to genotyping and map errors

Bioinformatics. 2015 May 15;31(10):1677-9. doi: 10.1093/bioinformatics/btu859. Epub 2015 Jan 7.

Abstract

Many applications in genetics require haplotype reconstruction. We present a phasing program designed for large half-sibs families (as observed in plant and animals) that is robust to genotyping and map errors. We demonstrate that it is more efficient than previous versions and other programs, particularly in the presence of genotyping errors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Animals
  • Chromosome Mapping
  • Genotyping Techniques / methods*
  • Haplotypes*
  • Pedigree*
  • Software*