Effects of glucomannan-enriched, aronia juice-based supplement on cellular antioxidant enzymes and membrane lipid status in subjects with abdominal obesity

ScientificWorldJournal. 2014;2014:869250. doi: 10.1155/2014/869250. Epub 2014 Dec 9.

Abstract

The aim of this study was to analyze the effects of a 4-week-long consumption of glucomannan-enriched, aronia juice-based supplement on anthropometric parameters, membrane fatty acid profile, and status of antioxidant enzymes in erythrocytes obtained from postmenopausal women with abdominal obesity. Twenty women aged 45-65 with a mean body mass index (BMI) of 36.1 ± 4.4 kg/m(2) and waist circumference of 104.8 ± 10.1 cm were enrolled. Participants were instructed to consume 100 mL of supplement per day as part of their regular diet. A significant increase in the content of n-3 (P < 0.05) polyunsaturated fatty acids in membrane phospholipids was observed, with a marked increase in the level of docosahexaenoic fatty acid (P < 0.05). Accordingly, a decrease in the n-6 and n-3 fatty acids ratio was observed (P < 0.05). The observed effects were accompanied with an increase in glutathione peroxidase activity (P < 0.05). Values for BMI (P < 0.001), waist circumference (P < 0.001), and systolic blood pressure (P < 0.05) were significantly lower after the intervention. The obtained results indicate a positive impact of tested supplement on cellular oxidative damage, blood pressure, and anthropometric indices of obesity.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antioxidants / metabolism*
  • Beverages*
  • Dietary Supplements*
  • Erythrocytes / enzymology*
  • Fatty Acids / metabolism
  • Female
  • Humans
  • Mannans / therapeutic use*
  • Membrane Lipids / metabolism*
  • Middle Aged
  • Obesity, Abdominal / drug therapy*
  • Obesity, Abdominal / enzymology
  • Photinia / chemistry*
  • Phytotherapy

Substances

  • Antioxidants
  • Fatty Acids
  • Mannans
  • Membrane Lipids
  • (1-6)-alpha-glucomannan