Really exasperating viral protein from HIV

Elife. 2015 Jan 9;4:e05169. doi: 10.7554/eLife.05169.

Abstract

Two new structures shed additional light on the nuclear transport of viral transcripts.

Keywords: HIV; RNA export; Rev protein; electron microscopy; human; infectious disease; microbiology; nuclear export; protein-RNA structure; viruses.

MeSH terms

  • HIV / physiology*
  • Humans
  • Karyopherins / metabolism
  • Protein Binding
  • Protein Multimerization
  • Receptors, Cytoplasmic and Nuclear / metabolism
  • Response Elements / genetics
  • Virus Replication
  • rev Gene Products, Human Immunodeficiency Virus / metabolism*

Substances

  • Karyopherins
  • Receptors, Cytoplasmic and Nuclear
  • exportin 1 protein
  • rev Gene Products, Human Immunodeficiency Virus